PSA levels should be almost undetectable after surgery or Radiation Therapy for Early Stage and Regional Prostate Cancer. When PSA levels don’t fall to zero or they elevate again after treatment, without spreading to other organs (M0), that means that the cancer is either recurrent or persistent. Following treatment will depend on the treatment you received before, either surgery or Radiation Therapy. If the patient only underwent surgery or Radiation Therapy, without ATD, it is considered castration naive M0 Prostate Cancer.
Familiarize yourself with castration naive recurrent or persistent Prostate Cancer M0 ADT options below and then Click Create My Conversation Guide to prepare a list of questions to discuss with your doctor. Always remember, the more you know, the more likely you’ll achieve your treatment goals.

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See If A Clinical Trial Is Right For You or Your Loved One
It is important to learn about clinical trials for your cancer type, their potential benefits, and risks, and then discuss all of your options with your doctors.
Answering a few questions in the Search Tool below will help you find relevant trials by Study Phase: Phase 1, Phase 2, or Phase 3 or by Study Type: Interventional or Observational.
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Understanding Clinical Trials
Is A Clinical Trial Right For You?

Informed Consent Protects Your Rights
What To Expect When You Participate
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Diagnosing Your Cancer
How Does a CT Scan Work?

Diagnosing Your Cancer
How Does a PET Scan Work?

Prostate Cancer Overview
Brachytherapy

Treatment Options for Localized Prostate Cancer
Common Questions Answered

Prostate Cancer Treatment: Targeted Therapy
An Easy to Understand Overview

Prostate Cancer Treatment: Immunotherapy
Common Questions Answered