Overview
Stage 4 Diffuse Large B-Cell Non Hodgkin Lymphoma is when the cancer has spread to one or more organs or tissues outside of the lymph node region such as the liver, lung, or bone marrow.
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- Stage 4 Diffuse Large B-Cell Non Hodgkin Lymphoma Diagnosis
Overview
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Diffuse Large B-cell Non-Hodgkin Lymphoma is the most common type of fast growing, Non-Hodgkin Lymphoma. It begins in your B lymphocytes, the white blood cells that help your body fight infection.
In Stage IV Diffuse Large B-Cell Lymphoma, the cancer has spread outside of the lymphatic system affecting at least one organ such as the liver, lung, or bone.
What Tests Will I Need and Why?
Blood tests and imaging such as a CT scan and/or a PET scan are done to understand your general health, confirm your diagnosis and determine your cancer stage.
Tissue analysis in the form of a core needle biopsy or excisional biopsy is typically done. In some cases, a bone marrow biopsy may be needed.
If your treatment team has not already performed tests to determine your cancer’s features, please ask your doctor when these tests will be performed.
Re-read this summary as needed and then tap, “Compare My Treatment Options Now“. Our unique Comparison Page will help you understand your FDA-approved treatment options including, who can help you pay for your treatment, where and how each is given and what side-effects you may experience.
National Institute of Health/ treatment-lymphoma
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Commonly Searched Questions
What Is Stage 4 Non-Hodgkin Lymphoma?
The cancer has spread to one or more tissues or organs outside the lymph system, such as the liver, lungs or bones, and may be found in lymph nodes near or far away from those organs.
Source: Cancer.gov
What’s the survival rate of Stage 4 Non-Hodgkin Lymphoma?
According to SEER data, Stage 4 Non-Hodgkin Lymphoma has a survival rate of 58.5%. For example, if the 5-year relative survival rate for stage 4 non-hodgkin lymphoma is 58.5%, it means that patients who have that cancer are, on average, about 58.5% as likely as patients who don’t have that cancer to live for at least 5 years after being diagnosed.
Source: Cancer.gov
What are the symptoms of Stage 4 Non-Hodgkin Lymphoma?
Signs and symptoms of non-Hodgkin’s lymphoma may include:
- Swollen lymph nodes in your neck, armpits or groin
- Abdominal pain or swelling
- Chest pain, coughing or trouble breathing
- Persistent fatigue
- Fever
- Night sweats
Source: Cancer.gov
What are the tests used to diagnose Stage 4 Non-Hodgkin Lymphoma?
The following tests and procedures can be used are:
- complete blood count (CBC) with differential
- blood chemistry studies
- bone marrow aspiration and biopsy
- cytogenetic analysis
- immunophenotyping
- molecular testing
Source: www.cancer.gov
What are the risk factors of Stage 4 Non-Hodgkin Lymphoma?
There are many types of lymphoma, and some of these factors have been linked only to certain types.
- Older age – Getting older is a strong risk factor for lymphoma overall, with most cases occurring in people in their 60s or older . But some types of lymphoma are more common in younger people.
- Gender – Overall, the risk of NHL is higher in men than in women , but there are certain types of NHL that are more common in women. The reasons for this are not known.
- Family History – Having a first degree relative (parent, child, sibling) with NHL increases your risk of developing NHL.
- Having a weakened immune system
Source: Cancer.gov
What are the treatment of Stage 4 Non-Hodgkin Lymphoma?
There are different types of treatment for patients with Non-Hodgkin Lymphoma such as:
- radiation therapy
- chemotherapy
- targeted therapy
- immunotherapy
- plasmapheresis
- stem cell transplant
- surgery
Source: Cancer.gov
