Overview
Chronic Myelogenous Leukemia is a slowly progressing blood and bone marrow disease that usually occurs during or after middle age, and rarely occurs in children.
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- Chronic Myelogenous Leukemia
Overview
Chronic Myelogenous Leukemia (CML) is a slowly progressing blood and bone marrow disease that usually occurs during or after middle age, and rarely occurs in children. In CML, too many blood stem cells become a type of white blood cell called Granulocytes shown here in orange . These Granulocytes are abnormal and do not become healthy white blood cells.
In Chronic Myelogenous Leukemia (CML), the disease is classified by phase: chronic phase, accelerated phase, or blastic phase. It is important to know your phase in order to make a treatment plan with your doctor.
What Tests Will I Need and Why?
Blood and Imaging tests are done to understand your general health and confirm your diagnosis.
TBiomarker testing is done in the blood and bone marrow to identify certain biomarkers such as Philadelphia Chromosome (Ph), which helps determine the best treatment option for you. Ph+ is found in most patients with CML.
You will also require a bone marrow biopsy and in some cases, a sample of spine liquid, to obtain more information about your diagnosis.
If your treatment team has not already performed tests to determine your cancer’s features, please ask your doctor when these tests will be performed. This information is critical to finding the best treatment option for you given your goals and lifestyle needs.
Re-read this summary as needed and then tap, “Compare My Treatment Options Now“. Our unique Comparison Page will help you understand your FDA-approved treatment options including, who can help you pay for your treatment, where and how each is given and what side-effects you may experience.
National Institute of Health/ treatment-leukemia
Commonly Searched Questions
What is Chronic Myelogenous Leukemia (CML)?
Chronic myelogenous Leukemia (also called CML or chronic granulocytic Leukemia) is a slowly progressing blood and bone marrow disease that usually occurs during or after middle age, and rarely occurs in children.
Source: www.cancer.gov
Chronic Myelogenous Leukemia (CML) survival rate
The average five-year survival in Chronic Myelogenous Leukemia (ALL) is 70.4%.
According to SEER data, Chronic Myelogenous Leukemia has a survival rate of 70.4%. For example, if the 5-year relative survival rate for a specific stage of chronic myelogenous leukemia is 70.4%, it means that patients who have that cancer are, on average, about 70.4% as likely as patients who don’t have that cancer to live for at least 5 years after being diagnosed.
Source: www.cancer.org
Chronic Myelogenous Leukemia (CML) symptoms
Signs and symptoms of chronic myelogenous leukemia include:
- feeling very tired
- weight loss for no known reason
- drenching night sweats
- fever
- pain or a feeling of fullness below the ribs on the left side
Source: www.cancer.gov
What are my treatment options for Chronic Myelogenous Leukemia (CML)?
There are six types of standard treatment are used:
- Chemotherapy
- Surgery
- Targeted therapy
- Immunotherapy
- High-dose chemotherapy with stem cell transplant
- Donor lymphocyte infusion (DLI)
Source: www.cancer.gov
Are there any other factors that might affect my prognosis?
The prognosis depends on the patient’s age, phase of CML, amount of blasts in the blood or bone marrow and the patient’s general health.
Source: www.cancer.gov
What are the tests used to diagnose CML?
The following tests and procedures can be used are:
- Complete blood count (CBC) with differential, blood chemistry studies
- FISH (fluorescence in situ hybridization)
- Bone marrow aspiration and biopsy
- Cytogenic analysis
Source: www.cancer.gov